In most cases, the odd-even column effect is small enough that it can be ignored. However, if the flux level of the exposure is above 10,000 or if the data was taken during those occasions when it was strong, users should think seriously about removing it. See Sec. .
The isaacp command features a recipe called oddeven, that takes care of removing the odd-even effect from a frame. While it works reasonably well to cover for most of the effect, it is no silver bullet. Check out the results coming out of this recipe. This recipe has been made available in eclipse since version 4.1.1 (December 2001).