Beyond the classic archetype: the relation between spiral structure and star formation in galaxies I will review our modern understanding of the nature of spiral structure and give a brief summary of spiral arm dynamics, focussing in particular on how gas flows driven by spiral features organize and rearrange the gas reservoirs in galaxies. As a result of gravitational torques exerted on gas by spiral perturbations, these structures bring recently accreted material from the outskirts of galaxies to their very centers, building the molecular reservoir for star formation on the way and contributing to the growth of black holes, the build-up of bulges and the feeding of central starburst activity. I will also describe the emerging picture for how spiral arms directly impact the amount, location, and regulation of star formation in disk galaxies. While these structures have long been appreciated for their vibrant, visual connection to the sites of recent star formation in nearby galaxies, we are only now beginning to understand the intimate role of spirals on the organization of gas down to the scales of giant molecular clouds -- the seeds of star formation. Following a summary of recent results from the spatially-extended cloud-scale PAWS survey of CO(1-0) emission in M51, I will highlight new avenues of exploration opening in the era of ALMA and MUSE.